Abstract:

Clinical data of 635 new smear-positive pulmonary tuberculosis patients hospitalized in Wuhan Pulmonary Hospital from January 2015 to December 2017 were collected. All of 1242 household contacts of those patients were screened for active pulmonary tuberculosis. The detection rate of active pulmonary tuberculosis among those household contacts was 1.69% (21/1242). The detection rates of active pulmonary TB in spouses, parents, children/other relatives among those household contacts were 1.51% (7/464), 3.66% (9/246) and 0.94% (5/532) respectively, with parents having the highest detection rate,the difference was statistically significant(χ ²=7.036,P=0.008). The detection rates of household contacts of patients with different M. fluorescens results (positive,+,++,+++ and ++++) were 0.60% (2/334), 0.50% (2/401), 1.11% (3/271), 4.32% (6/139), and 8.25% (8/97) respectively,the difference was statistically significant(χ ²=37.232,P=0.000); The detection rate of active pulmonary tuberculosis in household contacts of new smear-positive patients with bronchial tuberculosis was 3.01% (10/332). Household contacts are more likely to be infected if the index case has high sputum bacilli counts or bronchial tuberculosis, or if contacts are parents of index case.

Key words: Tuberculosis,pulmonary, Contact tracing, Family, Outcome assessment (health care)