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中国防痨杂志 ›› 2017, Vol. 39 ›› Issue (10): 1073-1079.

• 论著 • 上一篇    下一篇

UGT1A1和CYP2E1基因多态性与一线抗结核药物所致肝损伤易感性研究

孙勤 刘轾彬 沙巍 肖和平   

  1. 200433 同济大学附属上海市肺科医院结核病临床研究中心 上海市结核(肺)重点实验室
  • 出版日期:2017-10-10 发布日期:2017-11-16
  • 通信作者: 沙巍 E-mail:shfksw@126.com

Association between UGT1A1 and CYP2E1 gene polymorphisms and susceptibility of first-line anti-tuberculous drug induced liver injury

SUN Qin, LIU Zhi-bin, SHA Wei, XIAO He-ping.   

  1. Clinic and Research Center of Tuberculosis, Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China
  • Online:2017-10-10 Published:2017-11-16
  • Contact: SHA Wei E-mail:shfksw@126.com

关键词: 结核, 药物性肝损伤, 多态性, 单核苷酸, 疾病遗传易感性

Key words: Tuberculosis, Drug-induced liver injury, Polymorphism, single nucleotide, Genetic predisposition to disease