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中国防痨杂志 ›› 2021, Vol. 43 ›› Issue (1): 87-90.doi: 10.3969/j.issn.1000-6621.2021.01.016

• 综述 • 上一篇    下一篇

结核病并发糖尿病治疗管理相关进展

杨敏, 付亮, 邓国防()   

  1. 518112 国家感染性疾病临床医学研究中心 南方科技大学附属深圳市第三人民医院肺病二科
  • 收稿日期:2020-12-03 出版日期:2021-01-10 发布日期:2021-01-12
  • 通信作者: 邓国防 E-mail:jxxk1035@yeah.net
  • 基金资助:
    “十三五”国家科技重大专项(2018ZX10715004-002-012)

Progress in the treatment and management of tuberculosis complicated with diabetes

YANG Min, FU Liang, DENG Guo-fang()   

  1. The Second Department of Pulmonary Diseases, National Clinical Research Center for Infectious Disease, Shenzhen Third People’s Hospital Affiliated to Southern University of Science and Technology, Shenzhen 518112, China
  • Received:2020-12-03 Online:2021-01-10 Published:2021-01-12
  • Contact: DENG Guo-fang E-mail:jxxk1035@yeah.net

摘要:

据估算,至2045年全球糖尿病患者可能会增长至7亿例,大约16%的结核病患者会并发糖尿病,结核病并发糖尿病(TB-DM)的双重负担会成为一个重大的全球性公共卫生问题。糖尿病(包括1型和2型)会增加活动性结核病的风险,与单纯结核病患者相比,TB-DM患者的治疗转归更差。糖尿病发病率的增长不但将增加罹患结核病的患病风险,还对结核病的治疗管理构成严重挑战。作者就TB-DM的双向筛查、相互影响、治疗和管理、药品相互作用等内容进行综述。

关键词: 结核, 糖尿病, 共病现象, 诊疗工作管理,医学, 药物疗法,联合, 药物相互作用, 综述

Abstract:

It is estimated that the number of patients with diabetes mellitus (DM) may increase to 700 million by 2045 in the world, and about 16% of tuberculosis patients may have DM, so the double burden caused by tuberculosis complicated with diabetes mellitus (TB-DM) will become a major global public health problem. Diabetes (including type 1 and type 2) can increase the risk of getting active tuberculosis. Compared with the patients who only have tuberculosis, the patients with TB-DM have worse treatment outcomes. Therefore, the increasing incidence of diabetes will not only increase the risk of having tuberculosis, but also pose a serious challenge to the treatment and management of tuberculosis. In this article, the authors reviewed the following issues related to TB-DM: the two-way screening, interactions of the two diseases, treatment and management, and drug interactions, etc.

Key words: Tuberculosis, Diabetes mellitus, Comorbidity, Practice management,medical, Drug therapy,combination, Drug interactions, Review