关键词: 糖尿病, 结核,肺, 共病现象, 疾病特征, 发病率, 数据说明,统计, 回顾性研究

Abstract:

Objective To investigate the incidence rate of pulmonary tuberculosis (TB) in hospitalized patients with diabetes mellitus (including type 1 and type 2 diabetes) and analyze the correlation between the activity of TB and the incidence of tuberculosis. Methods We retrospectively reviewed the routine chest imaging and clinical data of 2648 patients with diabetes in our hospital from January 2018 to December 2019. We then calculated the incidence rate of pulmonary tuberculosis in diabetic patients. The basic characteristics, the level of glycosylated hemoglobin and the status of diabetes treatment were compared between active tuberculosis group and inactive tuberculosis group. Results Of the 2648 patients with diabetes, 2585 patients had no evidence of tuberculosis, accounting for 97.62% (2585/2648); 31 patients complicated with active tuberculosis, accounting for 1.17% (31/2648); 32 patients complicated with inactive tuberculosis, accounting for 1.21% (32/2648). Active tuberculosis and inactive tuberculosis were mainly male, accounting for 90.32% (28/31) and 84.38% (27/32)respectively. The average age of active tuberculosis patients was (51.16±13.06) years old, of inactive tuberculosis patients was (61.78±12.88) years old. The difference between the two groups was statistically significant (t=-3.236, P=0.002). The average glycosylated hemoglobin of patients with active tuberculosis was (9.18±2.85) %, of patients with inactive tuberculosis was (8.05±1.69) %. There was no significant difference between the two groups (t=1.884, P=0.070). Conclusion Diabetes inpatients have a high proportion of concurrent tuberculosis, most of them are male. We should pay attention to the screening and follow-up of pulmonary tuberculosis in diabetic inpatients; the correlation between blood glucose control level and tuberculosis activity of diabetic patients needs to be further confirmed.

Key words: Diabetes mellitus, Tuberculosis,pulmonary, Comorbidity, Disease attributes, Incidence, Data interpretation,statistical, Retrospective studies