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中国防痨杂志 ›› 2019, Vol. 41 ›› Issue (9): 1021-1024.doi: 10.3969/j.issn.1000-6621.2019.09.020

• 综述 • 上一篇    

肺结核患者密切接触者潜伏性结核感染预防性治疗研究进展

任哲雯,成君,徐彩红,张慧()   

  1. 102206 北京,中国疾病预防控制中心结核病预防控制中心
  • 收稿日期:2019-08-12 出版日期:2019-09-10 发布日期:2019-09-06
  • 通信作者: 张慧 E-mail:zhanghui@chinacdc.cn
  • 基金资助:
    “十三五”国家科技重大专项(2017ZX10201302)

Progression of preventive treatment of latent tuberculosis infection in close contacts of patients with tuberculosis

Zhe-wen REN,Jun CHENG,Cai-hong XU,Hui ZHANG()   

  1. National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
  • Received:2019-08-12 Online:2019-09-10 Published:2019-09-06
  • Contact: Hui ZHANG E-mail:zhanghui@chinacdc.cn

摘要:

肺结核患者密切接触者是结核分枝杆菌感染和活动性肺结核发病的高危人群之一,对处于潜伏感染状态的密切接触者进行预防性治疗可以降低其结核病的发病率。作者针对目前已报道的在潜伏感染的肺结核患者密切接触者中开展预防性治疗的研究展开讨论,以明确该人群预防性治疗的研究进展,以及存在的问题和对策,为将来进一步研究探索提供建议。

关键词: 结核,肺, 接触者追踪, 潜伏性结核病, 抗生素预防, 综述文献(主题), 预防性治疗

Abstract:

Close contacts of tuberculosis patients is one of the high-risk groups for Mycobacterium tuberculosis infection and active tuberculosis. Preventive treatment of close contacts with latent infection can decrease the incidence of tuberculosis. This study discusses the current researches on preventive treatment in close contacts with latent tuberculosis infection to clarify the research progress and existing problems of preventive treatment in this group, and to provide suggestions for further researches and explorations in the future.

Key words: Tuberculosis,pulmonary, Contact tracing, Latent tuberculosis, Antibiotic prophylaxis, Review literature as topic, Preventive treatment