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中国防痨杂志 ›› 2013, Vol. 35 ›› Issue (11): 858-864.

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抗结核药物所致肝损伤相关危险因素及临床处置对策

雷建平 吴雪琼 张文宏   

  1. 330008 江西省胸科医院(雷建平);解放军第三О九医院全军结核病研究所(吴雪琼);复旦大学附属华山医院感染科(张文宏)
  • 收稿日期:2013-09-13 出版日期:2013-11-10 发布日期:2013-11-03

Risk factors related to anti-tuberculosis drug-induced liver injury and countermeasures of clinical treatment

LEI Jian-ping, WU Xue-qiong, ZHANG Wen-hong   

  1. Chest Hospital of Jiangxi Province,Nanchang  330008,China
  • Received:2013-09-13 Online:2013-11-10 Published:2013-11-03

摘要: 抗结核治疗中药物性肝损伤较为常见,其发生原因复杂多样,应熟悉相关危险因素,完善实验室检查发现手段,探讨合理的调整抗结核治疗、护肝治疗及停药措施,努力实现治疗和管理措施与时俱进。

关键词: 肝炎,中毒性, 抗结核药, 危险因素

Abstract: The anti-tuberculosis drug-induced liver injury is common. It has complex and diverse reason. Its risk factors should be known, the laboratory examination methods should be improved. Explore the reasonable adjustment of anti-tuberculosis treatment, therapy for the liver protects and the measure of stop anti-tuberculosis medicine. Make the measure of tuberculosis treatment and management to keep pace with the times.

Key words: Hepatitis, toxic, Antitubercular agents, Risk factors