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中国防痨杂志 ›› 2021, Vol. 43 ›› Issue (7): 751-754.doi: 10.3969/j.issn.1000-6621.2021.07.019

• 短篇论著 • 上一篇    

一起学校利福平耐药肺结核聚集性疫情的调查分析

常俊丽, 张建宏, 章瑛*(), 张海芳, 凡鹏飞, 李秋华, 丁雪玲   

  1. 323600 浙江省丽水市云和县疾病预防控制中心疾病预防控制科(常俊丽、张建宏、章瑛),丽水市疾病预防控制中心重大疾病预防控制所(张海芳、凡鹏飞、李秋华),丽水市缙云县疾病预防控制中心传染病防制科(丁雪玲);
  • 收稿日期:2021-04-21 出版日期:2021-07-10 发布日期:2021-07-09
  • 通信作者: 章瑛 E-mail:yh-zhangying@163.com

Investigation and analysis of a cluster epidemic of rifampicin-resistant tuberculosis in a school

CHANG Jun-li, ZHANG Jian-hong, ZHANG Ying*(), ZHANG Hai-fang, FAN Peng-fei, LI Qiu-hua, DING Xue-ling   

  1. Department of Disease Control, Center for Disease Control and Prevention of Yunhe County, Lishui City, Zhejiang Province, Yunhe 323600, China
  • Received:2021-04-21 Online:2021-07-10 Published:2021-07-09
  • Contact: ZHANG Ying E-mail:yh-zhangying@163.com

摘要:

2020年5月,浙江省丽水市云和县和缙云县先后报告了3例活动性肺结核学生病例,通过现场流行病学调查结合后续的实验室检测结果,最终判定3例学生病例为一起原发性利福平耐药肺结核聚集性疫情。本次疫情处置提示:采取多种方式加强学校结核病防治知识健康教育,全面推进和强化初中、高中新生入校结核病健康筛查,在现有诊断技术和检测能力下对耐药结核病早诊断、早治疗等是提高学校耐药结核病疫情精准防控能力的重要措施;同时,加强辖区内网络平台疫情监测及建立结核病耐药菌株基因库平台是耐药结核病溯源分析最有力的依据。

关键词: 结核, 利福平, 抗药性, 疾病暴发流行, 学校

Abstract:

In May 2020, three student cases of active tuberculosis were reported in Yunhe County and Jinyun County of Lishui City in Zhejiang Province. Through field epidemiological investigation and follow-up laboratory test results, it was finally confirmed that the three student cases were a case of primary rifampicin-resistant tuberculosis aggregation epidemic. It is suggested that: taking various ways to strengthen the health education of tuberculosis prevention and control knowledge in schools, comprehensively promoting and strengthening the tuberculosis health screening of junior high school and senior high school freshmen, and early diagnosis and treatment of drug-resistant tuberculosis under the existing diagnostic technology and detection ability are important measures to improve the accurate prevention and control ability of drug-resistant tuberculosis in schools; At the same time, strengthening the network platform epidemic monitorning and the establishment of tuberculosis drug-resistant strains gene bank platform are the most powerful basis for drug-resistant tuberculosis traceability analysis.

Key words: Tuberculosis, Rifampin, Drug resistance, Disease outbreaks, School