关键词: 结核,肺, 生活质量, 问卷调查, 结果与过程评价(卫生保健), 因素分析,统计学, 欧洲五维度生命质量量表

Abstract:

Objective To investigate the quality of life of patients with tuberculosis, and analyze its influencing factors. Methods A total of 336 tuberculosis patients hospitalized in Beijing Chest Hospital affiliated to Capital Medical University and the Eighth Medical Center of the People’s Liberation Army General Hospital from January to December 2018 were randomly selected as subjects in this study. The tuberculosis patients were investigated with questionnaires and European quality of life-5 dimensions (EQ-5D). A total of 336 questionnaires were distributed and 336 were actually recovered, with a response rate of 100.00%. There were 270 valid questionnaires with an effective rate of 80.36%. SPSS 19.0 software was used for data entry and statistical analysis, and Chi-square test and logistic regression were used for multivariate analysis. Results The visual analogue scaling (VAS) score of 270 tuberculosis patients was 73.59±18.24, and the EQ-index score was 0.78±0.29. The proportion of difficulty in five-dimension measurement was between 21.5% (58/270) and 30.7% (83/270). Logistic regression analysis showed that the risk factors of self-action ability were age (OR=4.291 (95%CI: 1.714-10.744)), conscious tuberculosis severity (OR=5.029 (95%CI: 1.810-13.971)), hemoptysis (OR=2.315 (95%CI: 1.036-5.173)). The risk factors of self-care ability were age (OR=6.652 (95%CI: 2.495-17.734)), conscious tuberculosis severity (OR=6.248 (95%CI: 2.099-18.597)). Risk factors for ability of daily activities included age (OR=3.028 (95%CI: 1.295-7.081)), conscious tuberculosis severity (OR=3.640 (95%CI: 1.471-9.010)), hemoptysis (OR=2.522 (95%CI: 1.146-5.554)). Risk factor for pain or discomfort was conscious tuberculosis severity (OR=7.923 (95%CI: 2.431-25.822)). Risk factors for anxiety or depression included conscious tuberculosis severity (OR=2.479 (95%CI: 1.007-6.102)) and psychological stress after illness (OR=5.112 (95%CI: 1.736-15.052)). Received tuberculosis-related health education (OR=0.259 (95%CI: 0.105-0.638); OR=0.227 (95%CI: 0.085-0.606)) was the protective factor of self-action ability and self-care ability. Conclusion Age and psychological stress are the main factors influencing the quality of life of tuberculosis patients. Receiving tuberculosis-related health education is the main protective factor affecting the quality of life of tuberculosis patients. We should strengthen the mental health management of tuberculosis patients, emphasize the importance of tuberculosis health education to improve the awareness of protection and prevention of patients, so as to improve the quality of life of tuberculosis patients.

Key words: Tuberculosis,pulmonary, Quality of life, Questionnaires, Outcome and process assessment (Health care), Factor analysis,statistical, European quality of life-5 dimensions