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中国防痨杂志 ›› 2019, Vol. 41 ›› Issue (10): 1096-1100.doi: 10.3969/j.issn.1000-6621.2019.10.006

所属专题: 骨关节结核外科治疗专题

• 论著 • 上一篇    下一篇

177例儿童骨关节结核的临床特征分析

杨磊,邹黎,杨攀易,杨晓东,江君,唐学阳()   

  1. 610041 成都,四川大学华西医院小儿外科
  • 收稿日期:2019-06-03 出版日期:2019-10-10 发布日期:2019-10-09
  • 通信作者: 唐学阳 E-mail:tangxueyang100@163.com

Analysis of clinical characteristics in 177 children with osteoarticular tuberculosis

Lei YANG,Li ZOU,Pan-yi YANG,Xiao-dong YANG,Jun JIANG,Xue-yang TANG()   

  1. Department of Pediatrics, West China Hospital, Sichuan University, Chengdu 610041, China
  • Received:2019-06-03 Online:2019-10-10 Published:2019-10-09
  • Contact: Xue-yang TANG E-mail:tangxueyang100@163.com

摘要:

目的 了解骨关节结核患儿的临床特点,为提出防治策略提供参考。方法 收集2013—2017年四川大学华西医院收治的177例骨关节结核患儿的临床资料,对其临床特点(包括年收治患儿例数、性别及年龄分布、结核病病灶部位、患者来源及地区)进行统计分析。结果 2013—2017年,四川大学华西医院收治的177例骨关节结核患儿中,四川省内患儿143例;平均年收治患儿35.4例;男111例,女66例,男∶女=1.68∶1;年龄1~14岁,平均(6.4±3.6)岁,其中幼儿及学龄前期(1~6岁)患儿占56.5%(100/177),学龄期(7~12岁)患儿占37.3%(66/177),12岁以上患儿占6.2%(11/177)。儿童骨关节结核发生部位依次为髋关节(59例)、脊柱(54例)、膝关节(42例)、踝关节(10例)。凉山彝族自治州、甘孜藏族自治州、阿坝藏族自治州及四川省内其他地区骨关节结核患儿例数分别占我院收治四川省内骨关节结核患儿总数的50.3%(72/143)、13.3%(19/143)、11.2%(16/143)和25.2%(36/143)。结论 四川大学华西医院收治的四川省内骨关节结核患儿以凉山彝族自治州、甘孜藏族自治州及阿坝藏族自治州儿童居多,是儿童骨关节结核早期防治的重点区域。且患病儿童中低龄儿童较多,是预防和筛查的重点人群。

关键词: 结核, 骨关节, 儿童, 疾病特征, 数据说明, 统计

Abstract:

Objective To understand the clinical characteristics of osteoarticular tuberculosis (TB) in pediatric patients and to provide reference for developing prevention and treatment strategy.Methods The clinical information and data of 177 children with osteoarticular tuberculosis admitted to the West China Hospital of Sichuan University from 2013 to 2017 were collected, including the number of cases admitted each year, sex and age distribution, lesion location of tuberculosis, source and area of the patients. Their clinical characteristics were analyzed.Results From 2013 to 2017, a total of 177 children with osteoarticular tuberculosis were admitted to the West China Hospital of Sichuan University and 143 cases out of them were from Sichuan Province. The average number of hospitalized patients each year was 35.4 cases; 111 patients were male while 66 patients were female, and the ratio of male to female was 1.68∶1; the age of the patients ranged from 1 year to 14 years with an average of 6.4±3.6 years, and the age-group distribution of the patients was as follows: the proportion of infant and before school age (1-6 years old) was 56.5% (100/177), school age (7-12 years old) was 37.3% (66/177) and aged 12 years old and above was 6.2% (11/177). The hip joint was the most commonly affected (59 cases), then followed by spine (54 cases), knee joint (42 cases) and ankle joint (10 cases). The number of the patients who were from Liangshan Yi Autonomous Prefecture, Ganzi Tibetan Autonomous Prefecture, Aba Tibetan Autonomous Prefecture and other areas in Sichuan Province accounted for 50.3% (72/143), 13.3% (19/143), 11.2% (16/143) and 25.2% (36/143), respectively.Conclusion The pediatric patients with osteoarticular tuberculosis admitted to the West China Hospital of Sichuan University are mainly from Liangshan Yi Autonomous Prefecture, Ganzi Tibetan Autonomous Prefecture and Aba Tibetan Autonomous Prefecture in Sichuan Province, so those areas are priority on early prevention and treatment of bone and joint TB. Furthermore, most of the pediatric patients with osteoarticular TB are young children, which is the key group population for TB prevention and screening.

Key words: Tuberculosis, osteoarticular, Child, Disease attributes, Data interpretation, statistical