耐多药结核病治疗指南的发展趋势

doi:10.3969/j.issn.1000-6621.2018.02.004

摘要/Abstract

摘要：

全球结核病发病率在2000—2017年略有下降,但在非洲和亚洲的部分地区仍控制不佳。耐多药结核病(multidrug-resistant tuberculosis,MDR-TB)的治疗现已成为全球公共卫生系统关注的重大问题,国际上对于MDR-TB最适宜的用药和治疗方案尚有争议。笔者总结了近年来WHO关于MDR-TB治疗的指南,对各指南的背景、主要建议、实施情况和发展趋势进行了分析。

关键词: 结核, 抗多种药物性, 指南, 药物疗法, 联合, 治疗应用, 评论

Abstract:

The global incidence of tuberculosis has declined marginally from 2000 to 2017, but it is still under poor control in parts of Africa and Asia. Multidrug-resistant tuberculosis (MDR-TB) has become a major concerned issue in the global public health system, and the optimum medications and treatment regimens for MDR-TB remain controversial. This review summarizes the treatment guidelines for MDR-TB in recent years and analyzes the background, specific recommendations, implementations and trends of these guidelines.

Key words: Tuberculosis, multidrug-resistant, Guidebooks, Drug therapy, combination, Therapeutic uses, Comment

张怡,孙峰,张文宏. 耐多药结核病治疗指南的发展趋势[J]. 中国防痨杂志, 2018, 40(2): 135-139. doi: 10.3969/j.issn.1000-6621.2018.02.004

Yi ZHANG,Feng SUN,Wen-hong. ZHANG. Trends in development of treatment guidelines for multidrug-resistant tuberculosis[J]. Chinese Journal of Antituberculosis, 2018, 40(2): 135-139. doi: 10.3969/j.issn.1000-6621.2018.02.004

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