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中国防痨杂志 ›› 2014, Vol. 36 ›› Issue (12): 1008-1010.doi: 10.3969/j.issn.1000-6621.2014.12.002

• 专家论坛 • 上一篇    下一篇

“儿童结核病零死亡率”:我们准备好了吗?

卢水华   

  1. 201508 上海市公共卫生临床中心结核科
  • 收稿日期:2014-10-28 出版日期:2014-12-10 发布日期:2015-02-28
  • 通信作者: 卢水华 E-mail:tubercle@shaphc.org

Towards zero childhood tuberculosis deaths: are we ready?

LU Shui-hua   

  • Received:2014-10-28 Online:2014-12-10 Published:2015-02-28
  • Contact: LU Shui-hua E-mail:tubercle@shaphc.org

摘要: 据WHO最新报道,每年至少有55万例儿童患结核病,每天至少200例儿童死于结核病这种可治之病。因此WHO从战略上提出了“全球儿童结核病零死亡率蓝图”。然而,儿童结核病的临床表现常缺乏特异性以及痰含菌量少,造成儿童结核病的诊断依然困难。儿童感染结核分枝杆菌后,年龄越小越容易进展为结核病,并发生结核性脑膜炎、结核全身播散甚至死亡等严重情况。中国是结核病高负担国家,儿童结核病疫情不容乐观。只有更加重视儿童结核病的诊断、治疗和防控,才有可能实现“儿童结核病零死亡率”。

关键词: 结核/死亡率, 儿童

Abstract: According to WHO estimation, there are more than half a million cases of tuberculosis in children occurring globally each year. Every day, more than 200 children under the age of 15 die of tuberculosis—a disease that is curable. WHO chart the roadmap for childhood tuberculosis: towards zero deaths. However, diagnosis of childhood tuberculosis remains difficult because of the atypical clinical symptoms and lack of sputum production in young children. Rates of progression from latent infection to active disease (including severe forms of the disease, such as meningitis, disseminated disease, or death as a result of M. tuberculosis) are higher in infants and young children. China ranks second among the high-burden countries for tuberculosis, children tuberculosis epidemic situation in China is not optimistic. Only by focusing on the common challenges for diagnosis, treatment, prevention and control of children tuberculosis, we can achieve the goal of zero tuberculosis deaths among children.

Key words: Tuberculosis/mortality, Child