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中国防痨杂志 ›› 2014, Vol. 36 ›› Issue (4): 274-278.doi: 10.3969/j.issn.1000-6621.2014.04.010

• 论著 • 上一篇    下一篇

抗酸染色在结核病病理诊断中的价值

张登才 刘斌 张丽华 史敏 苏勤军 杨艳丽 钱震 哈英娣   

  1. 730050  解放军兰州军区兰州总医院病理科［张登才（兰州大学基础医学院病理学研究所在读研究生）、刘斌、史敏、苏勤军、杨艳丽、钱震、哈英娣］；兰州石化总医院病理科（张丽华）
  • 收稿日期:2013-03-04 出版日期:2014-04-10 发布日期:2014-05-02
  • 通信作者: 刘斌 E-mail:liumb@189.cn

The value of acid-fast staining in pathological diagnosis of tuberculosis

ZHANG Deng-cai, LIU Bin, ZHANG Li-hua, SHI Min, SU Qin-jun, YANG Yan-li, QIAN Zhen, HA Ying-di   

  1. Department of Pathology, Lanzhou General Hospital of Lanzhou Military Command of Chinese People’s Liberation Army, Lanzhou 730050, China ( *Master’s Degree, Institute of Pathology, College of Basic Medical Sciences, Lanzhou University，Lanzhou  730000, China)
  • Received:2013-03-04 Online:2014-04-10 Published:2014-05-02
  • Contact: LIU Bin E-mail:liumb@189.cn

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摘要： 目的 探讨抗酸染色在结核病病理诊断中的意义。方法 回顾性分析2000—2012年兰州军区兰州总医院病理诊断结核病并有抗酸染色结果的914例（男485例，女429例）患者的病理资料。使用SPSS 20.0软件进行统计学处理，以χ2检验对计数资料进行统计分析，P<0.05为差异有统计学意义。结果 914例结核病患者结核分枝杆菌抗酸染色阳性率为31.95％（292/914）。支气管结核和肠结核患者结核分枝杆菌抗酸染色阳性率分别为48.24％（41/85）和58.06％（18/31），高于肺结核抗酸染色阳性率（33.33％，72/216），差异均有统计学意义（χ2值分别为5.777、7.159，P值均＜0.05）；结核性胸膜炎（19.78％，18/91）、脊柱结核（16.52％，19/115）和关节结核阳性率（12.00％，6/50）低于肺结核患者结核分枝杆菌抗酸染色阳性率（33.33％，72/216），差异均有统计学意义（χ2值分别为5.676、10.640和8.916，P值均＜0.05）。男、女患者结核分枝杆菌抗酸染色阳性率分别为30.93%（150/485）和33.10%（142/429），性别对抗酸染色结果差异无统计学意义（χ2=0.494，P>0.05）。结论 抗酸染色仍是诊断结核病的有效确切手段，病变部位不同，抗酸染色阳性率亦有差异。

关键词: 结核/诊断, 染色与标记

Abstract: Objective To investigate the value of acid-fast staining in pathological diagnosis of tuberculosis(TB). Methods  Nine hundred and fourteen TB cases (485 male, 429 female) with acid-fast staining admitted to our hospital from 2000 to 2012 were analyzed retrospectively. SPSS 20.0 software was used for statistical analysis. Statistical comparisons were performed usingχ2 test, and P value less than 0.05 was considered statistical significant. Results  Among the 914 patients positive rate of acid-fast staining was 31.95% (292/914). The positive rates of endobronchial TB, intestinal TB were 48.24％(41/85),58.06％(18/31) respectively，which were higher than that of pulmonary TB (33.33%, 72/216) with statistical significant differences (χ2=5.777, P<0.05; χ2=7.159, P<0.05); while the positive rates of pleural TB, spinal TB and osteoarthral TB were 19.78％(18/91),16.52％(19/115),12.00％(6/50) respectively, which were lower than that of pulmonary TB, with statistical significant differences (χ2=5.676, P<0.05; χ2=10.640, P<0.05; χ2=8.916, P<0.05). The positive rates in male and female patients were 30.93% (150/485) and 33.10% (142/429) respectively, with no statistical significance difference（χ2=0.494，P＞0.05）. Conclusion  Acid-fast staining is still an effective method for the diagnosis of TB. The positive rate can be affected by the lesion site.

Key words: Tuberculosis/diagnosis, Staining and labeling

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